Amphetamines: Correlation of Activity with Stability of Molecular Complexes
نویسندگان
چکیده
منابع مشابه
Amphetamines: correlation of activity with stability of molecular complexes.
Molecular complexes have been prepared from several biologically active methoxyamphetamines and 1,4-dinitrobenzene. The association constants of these complexes, determined by nuclear magnetic resonance measurements, correlate linearly with the threshold hallucinogenic dose in humans.
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comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.
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15 صفحه اولCorrelation of psychotomimetic activity of phenethylamines and amphetamines with 1-octanol-water partition coefficients.
In an attempt to relate the hallucinogenic potencies in man of some biologically important amphetamines and phenethylamines, the 1-octanol-water partition coefficients for 11 amphetamines were determined. Using these values and published Hansch pi constants, the log P for 17 additional amines was estimated. It was found that lipophilicity, as measured by the log of the partition coefficient, ma...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1972
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.69.6.1346